Endocrine Abstracts

Background: Hypercalcaemia in endocrine patients often poses diagnostic challenge, with hyperparathyroidism and familial hypocalciuric-hypercalcaemia(FHH) being common differentials. This case-report presents unique and complex aetiology, underscoring need for comprehensive evaluation.Case-Description: We present case of 57-year-old Caucasian-woman referred to our clinic with persistently elevated calcium and parathyroid...

Introduction: Parathyroid cancer is a rare endocrine malignancy and constitutes 0.005% of all cancers. It can recur in 50% of cases. The first recurrence commonly occurs within 3 years of the original diagnosis. Hypercalcaemia is the main cause of morbidity and mortality. We present a case of a 62-year-old male patient who had an atypical lung nodule recurrence with normal calcium and PTH levels, six years following resection of a functioning parathyroid cancer.<p class="a...

Introduction: Pathological fractures are uncommon in young patients and raise concern about malignancy. Brown tumour (osteitis fibrosa cystica) is a rare benign resorptive bone lesion reported in approximately 3% of patients with primary hyperparathyroidism (PHPT). These have become uncommon in contemporary practice and have the potential to be misdiagnosed because of radiological similarities to other bone diseases especially malignancy.We present a case where the first prese...

Introduction: Insulinoma a neuroendocrine tumour is diagnosed by inappropriately raised Insulin concentrations during a spontaneous or induced episode of hypoglycaemia. A provocative 72-h supervised fast is done to evaluate suspected inappropriate insulin secretion. Our aim is to see if it is feasible for a shorter duration of fast is enough to confirm Insulinoma.Method and results: In our Trust we analysed retrospectively in the last 10 years, ...